| A Case of Letterer-Siwe Disease. |
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Kir Young Kim, Ki Young Lee, Kook Hoon Ko, Geukdong KO |
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Dept, of Pediatrics Yonsei Medical School |
| Letterer-Siwe氏病의 一1 例 |
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金吉英, 李琦寧, 金鍾源, 高克勳 |
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延世大學校 醫科大學 小兒科學敎室 |
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| Abstract |
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This is a report of a 10 months-old male with Letterer-Siwe disease. The patient illustrated the classical clinical features of the disease, including maculopapular rash, hemorrhagic manifestations, anemia,diarrhea, marked enlargement of the spleen & liver, and susceptibility to secondary infection. Most of these signs developed soon after birth. (Fig. 1,2, & 3) Diagnosis was confirmed by microscopic examination, of skin biopsy and bone marrow aspiration. (Fig. 4 & 5) The patient received intensive antibiotic and corticosteroid therapy without improvement.
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