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Phagocytic Activity of Leucocytes in Malnutrition

Journal of the Korean Pediatric Society 1965;8(5):9-14.
Published online November 30, 1965.
Phagocytic Activity of Leucocytes in Malnutrition
chul kyu Kim
Dept, of Pediatrics, College of Medicine, Seoul National University.
營養失調症 兒童에 있어서의 中性 暗好 顆粒 血球의 食菌機能에 關하여
서 울大學校 醫科大學小兒科學敎室
It is generally believed that malnourished patients are more prone to bacterial infection than normal healthy individuals. Increased susceptibility to infection has been attributed to depressing the reticuloendothelial systems, producing a diminution in the number of cells released into bloodstream, a reduction in antibody production, and a decrease in phagocytic activities as well as other functions. Phagocytosis of npn-pathogenic staphylococcus albus has been studied in 13 well nourished subjects and in 23 patients with chronic malnourished state. The opsonocytophagic Index, that is the mean ingestion of the staphylococci by neutrophil polymor phonuclear leukocyte, was decreased in malnourished group compared with well nourished group. (4.99:7. 64) The phagocytosis was not related to age and anemia, but it was increasing proportionally to serum protein level.

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