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Original Article
A Clinical Study on the Liver Cirrhosis in Children: Review of 40 Cases
Je Woo Kim, Ki Sup Chung, Chan Il Park
Clin Exp Pediatr. 1995;38(11):1506-1514.   Published online November 15, 1995
Purpose : Liver cirrhosis is relatively uncommon disease in childhood, but the overall prevalence rate and etiology of the liver cirrhosis in children were uncertain in Korea. This clinical study was undertaken to help pediatricians manage the patients properly by investigating the etiology, clinical findings and the outcome on 40 pediatric patients with liver cirrhosis. Methods : This study was conducted...
Case Report
Pancreatic Islet-cell Adenoma
Ji Hong Kim, Ho Seong Kim, Duk Hi Kim, Hyun Yee Im, Chan Il Park
Clin Exp Pediatr. 1993;36(6):870-876.   Published online June 15, 1993
Pancreatic islet cell adenoma is a benign tumor of pancreatic β-cell and a rare cause of hyperinsulinemic hypoglycemia in chidren. The autors experienced a case of pancreatic islet cell adenoma(Insulinoam) in a 11 year and 8 month old male who had frequent loss of consciousness and seizuere. Enucleation was done after localiztion of tumor by selective celiac artery angiography and abdominal...
Original Article
A case of primary hepatocellular carcinoma following vertical transmission of hepatitis B virus in a child.
Soo Kyoung Lee, Ki Sup Chung, Sun Won Hong, Chan Il Park
Clin Exp Pediatr. 1991;34(11):1573-1580.   Published online November 30, 1991
Authors experienced a case of primary hepatocellular carcinoma in a 7 year 9 month old male patient, who was admitted to our hospital due to abdominal pain on right upper quadrant and anorexia during last two months. On family history, his mother was HBs Ag and HBe Ag carrier. On past history, he was admitted to a hospital due to persistant jaundice at...
A Case of Massive Thymic Hyperplasia.
Hye Kyung Bae, Jung Kyu Suh, Jae Seung Yang, Baek Keun Lim, Yeun Kee Kim, Chan Il Park
Clin Exp Pediatr. 1988;31(11):1516-1521.   Published online November 30, 1988
We have experienced a case of massive thymic hyperplasia in 2 months old female with about 1 month’s history of upper respiratory tract infection and inspiratory stridor. The chest X-ray and chest CAT scan examination revealed superior mediastinal huge mass and so surgical resection and pathologic examination were perfermed because of clinical suspicion of pathologic mass. The pathologic finding of mass showed massive thymic...
A Clinical and histopathological Studies of congenital Extrahepatic Biliary Atresia.
Kweon Ha Son, Ki Sup Chung, Euh Ho Whang, Chan Il Park
Clin Exp Pediatr. 1988;31(4):436-445.   Published online April 30, 1988
A clinical assessment of the 30 patients with extrahepatic biliary atresia who were admitted to the Department of Pediatrics and pediatric Surgery, Yonsei University College of Medicine from January, 1979 to January, 1987 was performed. In 21 patients who underwent hepatic portoenterostomy, the relationship between outcome and surgery was analyzed. Finally, collelations between lonterm prognosis and the histopathology of biopsied liver tissue, postoperative bile...
The Effect of Thyroid Hormone Deficiensy on Growth Hormone Levels.
Duk Hi Kim, Chan Il Park
Clin Exp Pediatr. 1988;31(1):64-71.   Published online January 31, 1988
Growth hormone and thyroid hormone are known to affect growth and development. The present experiment was undertaken to assess GH levels in the serum and pituitary gland of prophylthiouracil (PTU) treated rats. The serum concentration of T4 were decreased during PTU treatment. Serum GH concentration and pituitary GH content were decresed with severity of hypothyroid status. After withdrawl of PTU, their levels were recovered gradually. Acidophil...
Case Report
A case of Myoclonic Encephalopathy associated with Neuroblastoma.
Jae Seung Yang, Chang Jun Coe, Han Gu Mun, Chan Il Park
Clin Exp Pediatr. 1985;28(9):926-930.   Published online September 30, 1985
We experienced a case of myoclonic encephalopathy, associated with occult neuroblastoma. This 14 months old male child manifested opsoclonus, myoclonic seizure as well as delayed development. This patient also, had neuroblastoma, which has been removed. After the surgical removal of the tumor, the opsoclons was not disappeared.
Original Article
A Clinical Study of Histiocytosis in Childhood.
Hee Jung Chung, Byung Soo Kim, Chan Il Park
Clin Exp Pediatr. 1984;27(3):253-264.   Published online March 31, 1984
A clinical study with particular emphasis on the result of chemotherapy has been made on. 34 cases of histiocytosis diagnosed at the Department of the Severance Hospital and Yonsei Cancer Center from January 1975 to December 1981. The results may be summarized as follows: 1) Among histiocytosis, HSC and LSD were each present in elevent cases, E-G in seven and HMR...
A Study of the Liver Biopsies in Infancy and Childhood.
Mea Young Chung, Ki Sup Chung, Chan Il Park, Yoo Bock Lee
Clin Exp Pediatr. 1982;25(7):656-668.   Published online July 31, 1982
To investigate the liver diseases affecting infancy and Childhood and to make a clinicopathologic correlation, a total of 105 liver biopsies were examined and following results were obtained. 1. Of the 105 liver biopsies, 94 cases were available for the study, and the male to female ratio of liver biopsies in infancy and childhood was 1.8 : 1. 2. Of...
Clinical and Histopathological Studies on Superficial Lymphadenopathy in Pediatric Ages.
Chong Ock Lee, Chan Il Park, Woo Hee Jung, In Joon Choi
Clin Exp Pediatr. 1982;25(6):560-570.   Published online June 30, 1982
The superficial lymph nodes may be enlarged in consequence of biologic or non-biologic antigenic stimuli, lymphoreticular maligna ntneoplasm, metastatic tumor or infiltrative disorders such as histiocytosis-X, and biopsy of the enlarged superficial lymph node is a time-honored diagnostic, therapeutic and follow-up tool. At present it is performed with ease and wideness. But in Korea there is no comprehensive studies about...
Case Report
A Case of Hypereosinophilic Syndrome.
Chul Young Lee, Ki Sup Chung, Byung Soo Kim, Chang Jin Kim, Chan Il Park
Clin Exp Pediatr. 1982;25(4):388-392.   Published online April 30, 1982
Marked eosinophilia is a common finding in many disease, occurring most frequently in allergic and parasitic conditions. A Separate syndrome characterized by peripheral eosinophilia and multisystem eosinophilic infiltration has been reported by many authors with a variety of diagnoses. In 1968, Hardy and Anderson proposed the term hypereosinophilic syndrome to encompass the entire group and in 1975, Chusid reported 14...
A Case of Acute(infantile) Gaucher's Disease.
Baek Keun Lim, Kwan Sub Chung, Jae Seung Lee, Kir Young Kim, Byung Soo Kim, Duk Jin Yun, Chang Jin Kim, Chan Il Park
Clin Exp Pediatr. 1981;24(10):982-990.   Published online October 15, 1981
A case of Acute infantile form of Gaucher's disease in Korean infant is described. The large cells characteristically found in the bone marrow and liver in Gaucher's disease have been investigated with electron microscope, as well as light microscope. The pertinent literature has reviewed briefly concerning the clinical and laboratory fingings, roentgenographic picture, pathogenesis, pathology, diagnosis and treatment of this...
Original Article
Hashimoto's Thyroiditis in childhood.
Hee Jung Chung, Back Keun Lim, Duk Hi Kim, Duk Jin Yun, Chan Il Park
Clin Exp Pediatr. 1981;24(8):752-759.   Published online August 15, 1981
Serum levels of T3, T4, TSH, 24-h RAIU and Thyroid antibodies were examined in 13 cases of chronic lymphocytic thyroiditis who were diagnosed at the pediatric department of Yonsei University hospital during the period from 1978 to 1980. The results were as follows: 1. The age distribution was dispersed between 8 and 15 years of age and all the cases...
Percutaneous Needle Liver Biopsy in Infancy and Childhood.
Ki Sup Chung, Young Mo Sohn, Duk Jin Yun, Chan Il Park
Clin Exp Pediatr. 1981;24(7):609-619.   Published online July 15, 1981
Thirty percutaneous liver biopsy and one liver necropsy were reviewed in Severance Hospital, Yonsei University from June 1979 to September 1980. This procedure is the safe and accurate means of diagnosing and studying liver diseases in the pediatric patients especially persistent conjugated hyperbilirubinemia, chronic liver disease, and some rare diseases (eg. Histiocytosis-X, Storage disease disease, Gilbert syndrome), The significance of...