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Type IV renal tubular acidosis(RTA) is due to renal tubular bicarbonate wasting
associated with mineralocorticoid deficiency. In its five subtypes, IV-4 is due to
pseudohypoaldosteronism(PHA) evidenced by increased plasma renin and aldosterone.
PHA is believed to result from distal tubular unresponsiveness to circulating aldosterone
and has normal renal and adrenal fuction.
Hypoaldosteronism can easily be suspected when the patient shows typical electrolyte
imbalance (hyponatremia coupled with... |
