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Purpose:We performed this study in order to investigate the effect of direct renin inhibition on an experimental animal model
with nephrotoxic serum nephritis and tried to give useful information for clinical research and renin inhibitor treatment.
Methods:Thirty BALB/c 6-week-old male mice were divided into 4 groups: control group (CO, n=5), control-treatment group
with aliskiren (CT, n=5), disease group (DO, n=10), and disease treatment... |