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Purpose : Estrogen deficiency causes sexual infantilism in Turner syndrome, which
could decrease the bone mineral density(BMD) since birth. This decreased BMD might
be contributed by the decreased growth hormone(GH) secretion. To improve the decreased BMD, estrogen therapy is recommended, especially after the pubertal age, but estrogen therpay during childhood can accelerate the epiphyseal fusion, resulting in shorter final height. There is... |
