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Granular lymphoblast which is characterized by the presence of clearly defined
azurophilic cytoplasmic granules are a relatively uncommon finding and indicate a
negative impact on prognosis of childhood ALL. Granular ALL is more common in FAB
L2 cases but there is no significant difference by immunophenotype and no specific
cytogenetic abnormality correlated with clinical significance of granular ALL has been reported.
We present a case... |
