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Original Article
Prophylactic Treatment of Anemia of Prematurity with Recombinant Human Erythropoietin and High Doses of Iron
Young Ho Lee, Ahn Hong Choi, Soon Yong Lee, Jeong Sook Park, Bong Keun Choi, Hyoung Shim Chang
Clin Exp Pediatr. 1997;40(3):361-367.   Published online March 15, 1997
Purpose : We conducted randomized study to determine whether high doses(6mg/kg/ day) of iron would exert a more supplemental effect than low doses(3mg/kg/day), and which regimen of recombinant human erythropoietin(rHuEPO) and iron would be more beneficial in the prophylactic treatment of anemia of prematurity. Methods : We randomly assigned 38 sick premature infants who were more likely than symptom-free premature infants requiring erythrocyte transfusions for...
Effect of Recombinant Human Erythropoietin on the Anemia of Premature Infants
Young Ah Lee, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong
Clin Exp Pediatr. 1996;39(5):631-640.   Published online May 15, 1996
Purpose : To determine whether the prophylactic treatment with recombinant human erythropoietin(rHuEPO) for the anemia of prematurity would reduce the need for blood transfusions. Methods : We randomly assigned 17 premature infants to therHuEPO group and the control group. For the rHuEPO group (n=9, birth weight=1210¡¾156 g, gestational age=31.7¡¾1.9wk), rHuEPO (400U/kg) was given three times a week for 4 weeks, plus iron (8 mg/kg/day) and vitamin...