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Original Article
Interaction of the mec Regulator Genes in Methicillin Resistant Staphylococcus
Young Choi, In Seok Lim, Tae Sub Shim, Mi Kyung Lee, Ae Ja Park
Clin Exp Pediatr. 1998;41(9):1224-1233.   Published online September 15, 1998
Purpose : Low-affinity penicillin-binding protein PBP 2a encoded by mecA is closely related to methicillin resistance in staphylococci, and the expression of PBP 2a is controlled by regulator elements encoded by mecR1 and mecI. Deletion or mutation which occurred in mecI is considered to be associated with constitutive production of PBP 2a. We investigated the distribution of mec regulator genes...
Clinical analysis of Serum and Urine N-Acetyl-β-D-Glucosaminidase (NAG) in Renal Disease
Yo Han Chung, In Seok Lim, Chul Ha Kim, Byoung Hoon Yoo, Tae Sub Shim
Clin Exp Pediatr. 1994;37(3):383-389.   Published online March 15, 1994
Recently, NAG activity has gained increasing importance as an aid in the diagnosis of renoparenchymal diseases. Elevation of urine NAG activity has been found to be an indicator of renoparenchymal diseases. To evaluate the diagnostic value of the NAG activity test in the renal disease, we carried out clinical study on 31 cases of renal disease patients who had been...
Asymptomatic human rotavirus infections during infancy and preschool period.
Hye Lim Jung, Byoung Hoon Yoo, Tae Sub Shim
Clin Exp Pediatr. 1989;32(11):1482-1488.   Published online November 30, 1989
Asymptomatic human rotavirus (HRV) infection rate was studied by comparing the rate of HRV excretion in diarrhea cases with that in nondiarhea group of children under preschool age. HRV antigen in stool was detected by enzyme-linked immunosorbent assay (ELISA) from children under 6 years of age who were admitted to Pediatric Department of Chung-Ang University Medical Center from November 1988 to mid-April 1989. 1) HRV antigen...
Analysis of Asymptomatic Proteinuria in School Children.
Chong Guk Lee, Tae Sub Shim, Dong Hwan Lee, Yong Soo Yun, Chang Jun Ko, Sa Jun Chung, Hyun Soon Lee, Sung Jae Suh, Pyung Nam Kim
Clin Exp Pediatr. 1989;32(9):1187-1194.   Published online September 30, 1989
Uriary mass screening program for the detection of proteinuria had been performed for a school- age population in the city of Seoul since 1981. Annually, about half million students, who comprised 3 different age group, corresponding to the averages of 11，14, and 17 years, had been examined. A systematic clinical evaluation was designed for students with proteinuria identified in the mass screening through ’87...
Physicial Growth of Children in Korean, 1985. -A comparison with 1975 Growth Data-
Tae Sub Shim, Kwang Wook Ko
Clin Exp Pediatr. 1986;29(3):233-254.   Published online March 31, 1986
The measurement of growth of individual children or of groups of children is one of the most sensitive and commonly used indicators of child health and nutrition. In many countries, children have been getting larger during the past 50 years because they are growing up faster and their adult size itself is increasing. Hence the weight-for-age and height-for-age standards have...
Case Report
A Case of Thanatophoric Dwarfism.
Hae Seong Lee, Wha Young Chung, Eung Sang Choi, Tae Sub Shim
Clin Exp Pediatr. 1983;26(9):922-927.   Published online September 30, 1983
Thanatophoric dwarfism is a lethal congenital chondrodystrophy characterized by diminished vertebral body height, a narrow thorax, and micromelia. This report presents the clinical, radiographic and autopsy findings of an experienced case of thanatophoric dwarfism detected prenatally by radiologic examination and discusses the differentiation of this disorder from other forms of congenital short limbed dwarfism.
An Autopsy Case of Agyria.
Young Ill Park, Joon Hee Oh, Tae Sub Shim, Je G Chi
Clin Exp Pediatr. 1979;22(9):799-802.   Published online September 15, 1979
An autopsy case of agyria in a newborn infant was reported. This neonate had her birth weight of 1.62kg after 40 weeks of gestation. The head circumference was 24cm(less than 3 percentile), and was slightly asymmetric. The brain weighed 60 grams. Fronto-occipital diameter was 7cm. And biparietal diameter was 6.5cm. Two small hemispheres were covered with opague congested leptomeninges, and...
A Pediatric Case of Korean Hemorrhagic Fever Confirmed by Fluorescent Antibody Technique.
Young Ill Park, Joon Hee Oh, Sang Woo Kim, Jin Young Choi, Tae Sub Shim
Clin Exp Pediatr. 1978;21(10):685-685.   Published online October 31, 1978
A case of Korean hemorrhagic fevery confirmed by fluorescent antibody technique in a 8years old boy was reported with a brief review of references.
Original Article
Chronic Myelocytic Leukemia in Childhood
Soon Yong Lee, Tae Sub Shim, Chang Yee Hong
Clin Exp Pediatr. 1967;10(9):487-494.   Published online September 30, 1967
Five cases of chronic myelocytic leukemia out of 96 cases of leukemia in childhood for 10 years, during January 1957 May 1967 are presented. Incidence of chronic myelocytic leukemia among 96 cases of all leukemias was 5.3% and sex ratio was male : female=2:3 with age range between 7 months~8 years of age. Chief complaints on admission were abdominal distention...
Clinical Studies on Leukemia in Childhood
Chang Yee Hong, Tae Sub Shim
Clin Exp Pediatr. 1967;10(5):261-268.   Published online May 31, 1967
Ninety cases of leukemia in children, aged 0~14 years, who were admitted Seoul National University Hospital during the period from Jan. 1957 to Dec. 1966, were analysed clinically and hematologically. The incidence of childhood leukemia was about 0.3% among the total patients who visited the hospital during the same period. There were 69 boys and 21 girls (sex ratio, 3.3:1)....
Atypical Patent Ductus Arteriosus
Young Hun Chung, Tae Sub Shim, Sung II Ahn, Chang Yee Hong
Clin Exp Pediatr. 1967;10(2):85-90.   Published online February 28, 1967
Four cases of atypical patent ductus arteriosus are presented. All of them had history of frequent upper respiratory infection and exertional dyspnea since infancy. Systolic murmurs were audible on the pulmanic area. On radiologic examination, heart was markedly enlarged, pulmonary segment was prominent and pulmonary vascular markings were increased at the proximal part. E.K.G. findings revealed high voltage of QRS...