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Original Article
Effects of Thioredoxin on Apoptosis-Inducing Neuronal Cell Injury
Hyunmi Kim, Gyoung Hee Kim, Yoon Song Lee
Clin Exp Pediatr. 1999;42(6):825-832.   Published online June 15, 1999
Purpose : Thioredoxin is an endogenous antioxidant. It regulates the activities of transcriptional factors such as NF-kB(nuclear factor kappa B)and AP-1(activator protein-1) and it increases the synthesis of cytokines, preventing cellular proliferation and apoptosis. The aim of this study was to clarify the role of thioredoxin on apoptosis-inducing neuronal cell injury. We investigated the protective effects of thioredoxin against apoptosis-inducing...
Cell Proliferation and Apoptosis in Heart of Trisomy 16 in Mice
Eun Jung Bae, Yong Soo Yun, Jung Sun Kim, Jeong-Wook Seo
Clin Exp Pediatr. 1999;42(5):621-630.   Published online May 15, 1999
Purpose : Although abnormal developments of cushion and atrioventricular septum have been suggested, the exact mechanism for the development of atrioventricular septal defect is not well known. We aimed to identify the role of cell proliferation and apoptosis on cardiac morphogenesis in trisomy 16 mice(an animal model for Down's syndrome in human). Methods : We examined the difference in cardiac...
Case Report
A Case of Pierre Robin Syndrome.
Hyun Hwa Kim, Hae Sook Cha, Byoung Hai Ahn, Young Hee You, Hyun Sook Lee
Clin Exp Pediatr. 1984;27(5):488-492.   Published online May 31, 1984
A case ef Pierre Robin Syndrome in a male baby who was born at the Korea Veterans Hospital was presented. After birth, dyspnea and feeding difficulty were developed. Physical examination revealed micrognathia, glossoptosis and cleft plate. Chromosomal analysis was normal pattern. This finding was compatible with Pierre Robin Syndrome. A brief review of literature was presented.