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Clinical Features of Twelve Coxiellemia Pediatric Patients in Korea

Journal of the Korean Pediatric Society 1992;35(9):1220-1225.
Published online September 15, 1992.
Clinical Features of Twelve Coxiellemia Pediatric Patients in Korea
Chuhl-Joo Lyu1, Dong Soo Kim1, Young Mo Sohn1, Ki Sup Chung1, Kir-Young Kim1, Won Young Lee2
1Department of Pediatrics, College of Medicine, Yonsei University, Seoul, Korea
2Department of Microbiology, College of Medicine, Yonsei University, Seoul, Korea
Coxiellemia 환아에 대한 임상적 고찰
유철주1, 김동수1, 손영모1, 정기섭1, 김길영1, 이원영2
1연세대학교 의과대학 소아과학교실
2연세대학교 의과대학 미생물학교실
Abstract
Coxiella burnetii is a rickettsial organism and extremely infectious for humans animals. The infection caused by this organism is endemic throughout the world. Although it has not been reported in Korea because of the nonspecific clinical manifestations, the difficulties in diagnosis, and the underestimate of this disease. Update this infection has been misdiagnosed as other disease. We experienced twelve cases of Coxiellemia pediatric patients. They are from 3 months to fifteen years old. The distribution of age was eve. All complained fever, there were rash in five(42%) and sore throat in four of twelve(33%), and cough in three(25%). The duratio of fever ranged from 3 days to about two months intermittently. At the diagnosis, lymphadenopathy was present in six(50%), hepatomegaly in six(50%) and splenomegaly in three(25%). Eight patients received rifampin only or with other antibiotics, but three patients were not treated with such antibiotics. All patients recovered completely. The fever and other symptoms were disappeared within seven days. We concluded that Korea is not remained the area beyond the endemic of Coxiellemia. We may find many cases of this disease if we try to find with interest, especially in patients with prolonged fever of unknown etiology and with abnormal hematologic findings.
Key Words: Coxiella burnetii


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