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A Case of Congenital Neuroblastoma: Diagnosed at Antenatal Perio

Journal of the Korean Pediatric Society 1992;35(12):1750-1755.
Published online December 15, 1992.
A Case of Congenital Neuroblastoma: Diagnosed at Antenatal Perio
Hye Young Kang1, Chuhl Joo Lyu1, Byung Soo Kim1, Seung Kang Choi2, Woo Hee Jung3, Soon Ae Chun4
1Department of Pediatrics, Yonsei University, College of Medicine, Yonsei Cancer Center, Seoul, Korea
2Department of Urology, Yonsei University, College of Medicine, Seoul, Korea
3Department of Pathology, Yonsei University, College of Medicine, Seoul, Korea
4Department of Radiology, Banwol Hospital, Banwol, Korea
재태기에 발견된 선천성 신경아세포종 1례
강혜영1, 유철주1, 김병수1, 최승강2, 정우희3, 전순애4
1연세대학교 의과대학 소아과학교실, 연세 암센터
2연세대학교 의과대학 비뇨기과학교실
3연세대학교 의과대학 병리학교실
4근로복지공사 방월병원 방사선과
Neuroblastoma is one of the most common tumors of childhood. It accounts for about 8% of all pediatric cancers. Because most children who present with this tumor are older than 1 year of age and have advanced disease, they have a poor prognosis in spite of intensive treatment. The patients with less than 1 year of age at the time of diagnosis a have favorable prognosis, even though they have distant metastasis to liver, skin and/or bone marrow with stage I or II. For the improvement in survival of patient with neuroblastoma, early detection of subclinical tumor is very important. However, it is very rare for neuroblastoma to be detected during intrauterine period and confirmed pathologically after birth as shown in this case. We experienced a case of 2 month-old-male baby who was suspected of neuroblastoma by antenatal sonographic examination at IUP 38 weeks, which was confirmed by postoperative pathological findings. The tumor was excised completely. The patient was closely observed for one and a half years and there were no evidence of recurrence. We report this case and review related literatures briefiy.
Key Words: Congenital Neuroblastoma, Diagnosed at during intrauterine period

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