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Three Cases of Purpura Fulminans

Journal of the Korean Pediatric Society 1993;36(5):725-732.
Published online May 15, 1993.
Three Cases of Purpura Fulminans
Sun Hee Suh, Hwang Min Kim, Jae Seung Yang, Baek Keun Lim
Department of Pediatrics, Yonsei University, Wonju College of Medicine, Wonju, Korea
급분성 자반병 3례
서선희, 김황민, 양재승, 임백근
연세대학교 원주의대 소아과학교실
Purpura fulminans is one of rare consumptive coagulopathy in children. The most common prediasposing conditions of purpura fulminans are infectious disease like streptococcal infection and chickenpox. This disease is characterized by ecchymotic lesions that are usually distributed symmetrically on the lower extremities and buttocks. These ecchymotic lesions undergo necrosis, unless there is effective treatment. We experienced 3 cases of purpura fulminans which improved almost completely after early heparin administration. In the case 1, a 12 month old girl, purpura fulminans developed during sepsis and gastroenteritis. In the case 2, a 4 month old boy, purpura fulminans developed during acute gastroenteritis and hepatitis. In the case 3, a 13 month old girl, purpura fulminans developed during sepsis. We reported 3 cases with a brief review of related literature.
Key Words: Purpura fulminans, DIC

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