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A Case of Unialteral Megalencephaly

Journal of the Korean Pediatric Society 1993;36(6):877-881.
Published online June 15, 1993.
A Case of Unialteral Megalencephaly
Woo Seok Kim2, Nam Soo Park2, Moo Young Song2, Un Jun Hyoung2, Jin Oh Lee2, Yong Seung Hwang1
1Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea
2Department of Pediatrics, Sung Ae General Hospital, Seoul, Korea
일측성 거대뇌증(Unilateral Megalencephaly) 1례
김우석2, 박남수2, 송무영2, 형운준2, 이진오2, 황용승1
1서울대학교 의과대학 소아과학교실
2성애병원 소아과
Abstract
The unilateral megalencephaly is a rare brain malfromation characterized by cerebral asymmetry and cortical dysplasia caused by faulty migration of the subependymal neuroblasts. We experienced a case of unilateral megalencephaly in a two day-old male with the chief complaint of asymmetric head appearance. Large left hemisphere with agyria, pachygyria. dilatation of lateral ventricle, and the thick cortex of the ipsilteral hemisphere were showed in brain MRI. Coinical findings in the case were intractable seizure, hemiparesis, and psychomotor retardatism. A review of literatures was also presented briely.
Key Words: Unilateral megalencephaly


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