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The Clinical Study of 10 Cases of Tsutsugamushi Fever

Journal of the Korean Pediatric Society 1994;37(5):689-694.
Published online May 15, 1994.
The Clinical Study of 10 Cases of Tsutsugamushi Fever
Dong Gyu Lee, Sung Hak Kim, Byung Keun Han, Kyung Ho Lee, Cheol Hee Hwang, Moon Ki Cho
Department of Pediatrics, St. Columban Hospital, Mokpo, Korea
소아 쯔쯔가무시열 10례의 임상적 고찰
이동규, 김성학, 한병근, 이경호, 황철희, 조문기
성 골롬반 병원 소아과
In Korean, there has been an increasing concern on rickettsiosis as a possile common cause of unkonwn febrile illness since Tsutsugamushi fever among koreans was reported first in1986. We experienced 10 cases of Tsutsugamushi fever ocurring in the Mokpo area during the period of 3 months(Oct. to Dec.) in 1990, which were diagnosed clinically and serologically by indirect immunofluorescent antibody test. The following results were obtained. The most frequent symptoms were fever(100%), headache(90%), chill(60%), conjunctival injection, and lymphadenopathy. Common laboratory findings were leukopenia (WBC<5000/mm3, 30%), elevated ESR(>20mm/hr, 30%), positive CRP(60%), and elevated ALT/AST. Antibody titers against R. tsutsugamushi ranged from 1:80 to 1:1,280, but they showed no antibody reaction to Hantaan virus and leptospira. All patients showed good response to antibiotic therapy with chloramphenicol.
Key Words: Tsutsugamushi fever

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