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A Clinical and Pathological Study of Recurrent Hematuria in Childhood

Journal of the Korean Pediatric Society 1994;37(8):1104-1110.
Published online August 15, 1994.
A Clinical and Pathological Study of Recurrent Hematuria in Childhood
Mi Jeong Kim, Jae Wook Ko, Young Jin Hong, Myung Ik Lee, Sun Wha Kim, Don Hee Ahn
Department of Pediatrics, National Medical Center, Seoul, Korea
무증상 반복성 혈뇨의 임상적 및 병리학적 고찰
김미정, 고재욱, 홍영진, 이명익, 김순화, 안돈희
국립의료원 소아과
The clinico-pathological observation was done on 28 children with recurrent hematuria, who had been admitted to the Pediatric ward of NMC from January 1981 to July 1991. The results were as follows; 1) Most of the children with recurrent hematuria were over 6 years of age (24 cases, 85.7%) and the sex ratio was about 2.5:1. 2) IgA nephropathy (17 cases, 60.7%) was the leading pathologic lesion and mild focal nonspecific glomerulonephritis (5 cases), membranous nephropathy (2 cases), minimal chage (2 cases), Alport syndrome (1 case), abnormal glomerular basement membrane (1 case) followed. 3) Types of recurrent hematuria were gross in 22 cases and microscopic in 6 cases. Flank pain was noted only 1 case. The prodromal events of hematuria were upper respiratory infection in 15 cases and severe exercise in 2 cases. 4) There were no significant differences in clinical features and laboratory findings between IgA nephropathy and other pathologic lesions, except for higher frequency of proteinuria in former group. 5) During the follow-up periods, three cases were resulted in chronic renal failure and they were two cases of IgA nephropathy Class IV and one case of Alport syndrome. And one case of IgA nephropathy was resulted in nephrotic syndrom.
Key Words: Recurrent hematuria, IgA nephropathy

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