| A Case of Burkitt's Lymphoma with Bilateral Renal Enlargement |
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Jun Hee Park1, In Kyu Lee1, Jong Woon Choi1, Soon Ki Kim1, Byong Kwan Son1, Jin Ju Kim2 |
1Department of Pediatrics, College of Medicine, In Ha University, Seongnam, Korea
2Department of Clinical Pathology, College of Medicine, In Ha University, Seongnam, Korea |
| 양측성 신장 비대를 동반한 버키트 림프종 1례 |
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박준희1, 이인규1, 최종운1, 김순기1, 손병관1, 김진주2 |
1인하대학교 의과대학 임상병리학교실
2인하대학교 의과대학 임상병리학교실 |
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| Abstract |
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Burkitt's lymphoma is a distinct pathologic entity characterized as a diffuse undifferentiated malignant lymphoma of B-lymphocyte origin.
We experienced a case of Burkitt's lymphoma with bilateral renal enlargement in which a 3 year-old male patient was admitted with complaints of abdominal distention and facial edema.
Laboratory examination revealed positivity for CD 19, CD 10, CD 20 and c-myc on flow cytometry, bilateral renal enlargement(10¡¿12cm in longitudinal length) on abdominal ultrasonogram and CT, malignant lymphoma of Buritt's type with prominent nucleoli and cytospin of cerebrospinal fluid.
Initially he showed tumor lysis syndrome and clinical stage D by Zigler(stage IV by Murphy) with CNS involvement.
After initial management with hydration, urine alkalinization and allopurinol, combination chemotherapy had been applied with the craniospinal radiotherapy according to the CCG 503 II regimane, with achievement of complete remission.
Thus we report a case of Burkitt's lymphoma with bilateral renal enlargement with a biref review of literatures. |
| Key Words:
Burkitt's lymphoma, Bilateral renal enlargement |
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