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Clinical Study on Insulin Dependent Diabetes mellitus

Journal of the Korean Pediatric Society 1995;38(6):827-834.
Published online June 15, 1995.
Clinical Study on Insulin Dependent Diabetes mellitus
Seog Beom Cho1, Kwang Rae Lee1, Chang Beom Shin1, Oh Kyung Lee3, Chong Duk Kim2, Oh Kyung Lee1
1epartment of Pediatrics, Chonbuk National university, Medical School, Shonju, Korea
2epartment of Pediatrics, School of Medicine, Wonkwang University, Iri, Korea
3Department of Pediatrics, Presbyterian Medical Center, Chonju, Korea
전라북도 지역 소아 연령에서 발생한 당뇨병의 임상적 고찰
조석범1, 이광래1, 신창범1, 이오경3, 김종덕2, 이오경1
1전북대학교 의과대학 소아과학교실
2원광대학교 의과대학 소아과학교실
3전주예수병원 소아과
: Insulin dependet diabetes mellitus(IDDM) is a rare disease in children, but it will progress rapidly and falls into a diabetic ketoacidosis or coma. Unfortunately, the characteristics and prevalence rate of children with IDDM are not well known in Korea. With a view to recognizing its importance, we studied clinical course of IDDM patients in Chonbuk province, Korea.
: From January 1981 to December 1993, 43 children with IDDM who were diagnosed at Presbyterian Medical center, Wonkwang University Hostpital and Chonbuk University Hospital were analyzed retrospectively.
: 1) The highest age incidence was in the age group of 11∼14years, and male to female ratio was 1:1.4, and seasonal distribution showed high incidence in winter. 2) Diabetic ketoacidosis was noted 28% of IDDM patients on admission. 3) Ketoacidosis was noted in 12 patients, and the cardinal symptoms were polydipsia, polyuria, and altered consciousness. 4) Laboratory findings at the ketoacidosis showed hyperglycemia, hemoconcentration, severe metabolic acilosis and hypocalcemia. 5) complications in 13IDDM patients follow-up for more the 2 years were diabetic ketoacikosis(5cases), infection(3cases), neuropathy, cataract, nephropathyu and the dosage of mean daily insulin requirement was 0.72±0.19u/kg.
: Many IDDM patients have suffered from ketoacidosis and chronic complications such as cataract, nephropathy. Therefore we need of the further studies of IDDM on a national scales.
Key Words: Insulin dependent diabetes mellitus, clinical study.

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