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Three Cases of Rotor Syndrome in Monozygotic Twin Brothers and Their Sister

Journal of the Korean Pediatric Society 1995;38(9):1270-1275.
Published online September 15, 1995.
Three Cases of Rotor Syndrome in Monozygotic Twin Brothers and Their Sister
Jin Hwa Jung, Jeong Ho Lee, Yong Sub Kim, Jong Dae Jo
Department of Pediatrics, Maryknoll Hospital, Busan, Korea
삼남매에서 발생한 Rotor 증후군 3례
정진화, 이정호, 김용섭, 조종대
부산메리놀병원 소아과
Abstract
We recently experienced three cases of Rotor syndrome in monozygotic twin brothers and their elder sister. The only clinical manifestation was persisting mild jaundice for several years. In all three cases serum bilirubin, mainly of direct reacting was increased with normal liver function and normal hepatic histology without pigmentation by needle liver biopsy. Indocyanine green test showed marked serum retention after 15 minutes and cholescintigraphy showed that liver was seen very faintly and persistent visualization of the cardiac pool and prominent kidney excretion after 60 minutes. A brief reviews of related literature was made.
Key Words: Rotor syndrome


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