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Growth and Neurodevelopmental Outcome on Very Low Birth Weight Infants During 2 Years

Journal of the Korean Pediatric Society 1996;39(5):641-651.
Published online May 15, 1996.
Growth and Neurodevelopmental Outcome on Very Low Birth Weight Infants During 2 Years
Eun Suk Kim, Jong Uk Kim, Oh Kyung Lee, Wan Soeb Kim
Department of Pediatrics, Presbyterian Medical Center, Chonju, Korea
극소체중아에서 교정연령 2년간 신체발육과 신경학적 발달에 관한 임상적 연구
김은숙, 김종욱, 이오경, 김완섭
전주예수병원 소아과
Abstract
Purpose
: By rapid development of neonatal intensive care from 1960, we are able to expect the long survival of the very low birth weight infants. But, there were high risk of poor growth, neurodevelopmental delay, deafness, and blindness in very low birth weight infants. So, it is important to follow-up after discharge. We try to compare normal term infants with very low birth weight infants by evaluating growth and neurodevelopmental outcome from living very low birth weight infants to corrected 2 years age.
Methods
: This study was performed on 55 very low birth weight infants with corrected age 6 months to 24 months who were admitted to the neonatal intensive care unit of Presbyterian Medical Center from August 1991 to December 1993 and 61 normal term infants with age 6 months to 24 months who had been born in Presbyterian Medical Center. We compared very low birth weight infants with normal term infants about growth and neurodevelopmental outcome at corrected age 6, 12, 18, 24 months. Weight, height and head circumference were measured. Developmental testing was performed using the BSID-Ⅱ(Bayley scales of infant development, Ⅱ). BSID-Ⅱ test provide Mental DevelopmentIndex (MDI) and Psychomotor Development Index(PDI). Motor handicap was graded as mild, moderate, or severe cerebral palsy. Sensorineural impairments were measured.
Results
: 1) Very low birth weight infants were low in weight, height and head circumference compared with normal term infants to corrected 2 years age. But, most cases were above 10 percentile 2) Very low birth weight infants were in low in BSID-Ⅱ's MDI(93.5±15.8) and PDI(91.3±17.9) compared with normal term infants. But, 76% of them were within normal range in MDI, 77% of them in PDI. 3) Seven patients of 55 very low birth weight infants had severe neurodevelopmental handicaps and three patients had severe cerebral palsy.
Conclusion
: We concluded that very low birth weight infants had significantly lower growth and BSID-Ⅱ than normal term infants, but majority of very low birth weight infants belong to normal range.
Key Words: Very low birth weight infants, Bayley scales of infant development-Ⅱ


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