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Antiphospholipid Syndrome Presented with Pulmonary Embolism and Deep Venous Thrombosis in Child

Journal of the Korean Pediatric Society 1996;39(5):722-726.
Published online May 15, 1996.
Antiphospholipid Syndrome Presented with Pulmonary Embolism and Deep Venous Thrombosis in Child
Ran Lee, Il Soo Ha, Hae Il Cheong, Yong Choi
Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea
폐색전증과 심부정맥혈전증을 보인 Antiphospholipid Syndrome 1례
이란, 하일수, 정해일, 최용
서울대학교 의과대학 소아과학교실
Abstract
Antiphospholipid syndrome is a thrombotic disorder and the serologic marker of the syndrome is antiphospholipid antibody(lupus anticoagulant, anticardiolpin antibody, or both). In a 13-year-old girl who presented with dyspnea, pulmonary embolism and femoral vein thrombosis were demonstrated by lung scan and abdominal ultrasonography. She had 3 out of 11 criteria for the diagnosis of SLE, such as thrombocytopenia, positive antinuclear antibody, low C3 and high anti-ds-DNA Ab, but did not meet whole criteria. And lupus anticoagulant was positive. She was treated with anticoagulants(heparin and wafarin) and prednisolone. Antiphospholipid antibody(lupus anticoagulant and anticardiolipin antibody) should be checked in children with thrombosis occurring without a known predisposing cause.
Key Words: Antiphospholipid syndrome, Pulmonary embolism, Deep vein thrombosis


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