| Myocardial Functions Estimated by Pulsed Doppler Echocardiography in Patientswith Chronic Renal Failure |
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Hyun June Huh, Byung Ho Choi, Myung Chul Hyun, Sang Bum Lee |
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Department of Pediatrics, College of Medicine, Kyungpook National University, Tague, Korea |
| 도플러 심에코 검사로 평가한 만성 신부전 환아들의 심근 기능 |
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허현준, 최병호, 현명철, 이상범 |
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경북대학교 의과대학 소아과학교실 |
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| Abstract |
Purpose
: The objectives of this study were to estimate myocardial functions in patients with
chronic renal failure by pulsed Doppler echocardiography, and investigate correlation between
Doppler and disease parameters.
Methods
: We studied 13 patients with chronic renal failure whose creatinine clearance rate
less than 25ml/min. Using pulsed Doppler echocardiography with curve following method, we
measured peak velocity, mean velocity, velocity-time integral and peak acceleration of aortic and
pulmonic flow velocity curves, and peak velocity, mean velocity, area of rapid filling wave in
early relaxation phase(E wave) and filling wave by atrial contraction in late relaxation phase(A
wave) and A/E ratios of the peak velocity and area. And we compared these parameters with
those of the normal controls, and then those with early chronic renal failure(less than 6 months
of disease duration) and those with late chronic renal failure(more than 6 months of disease
duration).
Results
: In patients with early chronic renal failure, peak velocity, flow time and area of E
wave of the mitral flow velocity curves were significantly decreased, and those of A wave were
markedly increased and resulted in marked increase in A/E ratios of the peak velocity and area
compared with those of the normal controls.
In patients with late chronic renal failure, mitral A/E ratio of the peak velocity continued to
be increased, and peak velocity, velocity-time integral and peak acceleration of the aortic flow
velocity curves were significantly decreased but pulmonary velocity- time integral was increased
markedly compared with those of the normal controls.
Conclusion
: Significant increase of mitral A/E ratio in patients with early chronic renal
failure and appearance of significant change in aortic flow velocity curves in patients with late
chronic renal failure suggest that abnormalities of myocardial relaxation seem to be present in
early phase of the chronic renal failure and continued into late phase but abnormalities of
myocardial contraction to appear on late phase of the chronic renal failure. |
| Key Words:
Myocardial functions, Pulsed Doppler echocardiography, Chronic renal failure |
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