| A Case of Reversible Biliary Pseudolithiasis After Ceftriaxone Therapy |
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Hye Kyung Lee1, Young Chang Kim1, Young Tong Kim2 |
1Department of Pediatrics, Soonchunhyang University Medical college, Chunan, Korea
2Department of Diagnostic Radiology, Soonchunhyang University Medical college, Chunan, Korea |
| Ceftriaxone사용후 병발된 Reversible Biliary Pseudolithiasis 1례 |
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이혜경1, 김영창1, 김영통2 |
1순천향대학교 의과대학 천안병원 소아과학교실
2순천향대학교 의과대학 천안병원 진단방사선과학교실 |
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| Abstract |
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Ceftriaxone, a potent third-generation semisynthetic cephalosporine, is widely used for
treatment various bacterial infections in children. There have been some reports that
transient appearance of gallbladder sludge was often demonstrated by abdominal sonography
in patients treated with ceftriaxone. Reversible biliary pseudolithiasis was used to
describe this phenomenon.
We present a case of biliary pseudolithiasis which appeared to be related to intravenous
ceftriaxone therapy in children who received ceftriaxone to treat meningitis. The
recommended ceftriaxone dose was 100mg/kg/day and a total duration of administrations
was 21 days. Abdominal sonographic examination showed nothing prior to antibiotic
therapy, however, multiple tiny hyperechogenic materials were observed in gallbladder on
day 7 of treatment. This patient did not demonstrate any symptoms. Follow-up abdominal
sonography examination revealed that gallbladder materials began to resolve spontaneously
on third day of posttherapy and complete resolution was observed on day 13
after cessation of ceftriaxone therapy. |
| Key Words:
Reversible Biliary Pseudolithiasis, Ceftriaxone |
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