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A Case of Myositis Ossificans Progressiva

Journal of the Korean Pediatric Society 1998;41(11):1601-1605.
Published online November 15, 1998.
A Case of Myositis Ossificans Progressiva
So Young Park, Su Jin Lee, Ji A Chung, Seung Joo Lee
Department of Pediatrics, College of Medicine, Ewha Womans University, Seoul, Korea
진행성 화골성 근염(Myositis Ossificans Progressiva) 1례
박소영, 이수진, 정지아, 이승주
이화여자대학교 의과대학 소아과학교실
So Young Park, Email: 1
Myositis ossificans progressiva(MOP) is a rare, slow progressive autosomal dominant disorder that principally affects children under the age 10 years. It is characterized by progressive fibroblastic proliferation, and subsequent calcification and ossification of subcutaneous fat, muscles, tendons, aponeuroses and ligaments. The disorder is often associated with symmetrical malformations of the digits, especially microdactyly or adactyly of the thumbs and great toes. The disease usually leads to extensive immobility and eventual disability. We experienced a case of MOP in a 2-year-old male child who showed multiple tender nodules on the left occipital, superior and inferior scapular, mid-back and upper buttock area and digital malformations and was treated with etidronate disodium. A brief review of related literatures is also presented.
Key Words: Myositis ossificans progressiva, Digital malformations

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