| Early Onset Hyperkalemia within 72 Hours after Birth in Extremely Preterm Infants |
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Young Pyo Chang |
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Department of Pediatrics, College of Medicine, Dankook University, Cheonan, Korea |
| 초극소 미숙아에서 생후 72시간 내에 발생하는 조기 발현 고칼륨혈증에 관한 연구 |
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장영표 |
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단국대학교 의과대학 소아과학교실 |
Correspondence:
Young Pyo Chang, Email: 1
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| Abstract |
Purpose
: The incidence of hyperkalemia and the factors contributing the serum potassium level within 72 hours after birth in extremely preterm infants were determined.
Methods
: The incidence of hyperkalemia and differences of clinical features between hyperkalemic(≥6.5mEq/L) and normokalemic(<6.5mEq/L) groups were determined by reviewing medical records of 53 extremely preterm infants born at less than 28 weeks gestation.
Results
: The mean birth weight and gestational age of were 912±186gram and 26.2±1.3weeks respectively. Thirty-six infants(67.9%) had at least one serum potassium level that exceeded 6.5mEq/L, and 15 infants with hyperkalemia(≥6.5mEq/L) had electrocardiographic abnormalities and eight infants had hyperkalemia-induced cardiac arrhythmia such as ven- tricular tachycardia, fibrillation and/or bradycardia. Serum potassium peaked in 13-36 hour postnatal age and the incidence of electrocadiographic abnormalities was highest in the 13-36 hour postnatal age group (P<0.05). Urine flow rate during the first 48 hours after birth was only significantly lower for hyperkalemic infants(P<0.05). Six infants with hyperkalemia died as a direct result of hyperkalemia-induced cardiac arrhythmia.
Conclusion
: Hyperkalemia frequently occurred within the first 72 hours of life in extremely premature infants. Serum potassium should be monitored closely to avoid life-threatening cardiac arrhythmia in these infants. |
| Key Words:
Hyperkalemia, Prematurity |
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