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A Case of Sporadic Caffey`s Disease(Infantile Cortical Hyperostosis) Without Mandibular Involvement

Journal of the Korean Pediatric Society 2000;43(9):1294-1299.
Published online September 15, 2000.
A Case of Sporadic Caffey`s Disease(Infantile Cortical Hyperostosis) Without Mandibular Involvement
Byoung Lae Oh, Seung Woo Paik, Wan Seob Kim
Department of Pediatrics, Presbyterian Medical Center, Chonju, Korea
하악골을 침범하지 않고 산발적으로 발생한 Caffey`s Disease 1례
오병래, 백승우, 김완섭
전주예수병원 소아과
Abstract
Caffey`s disease(infantile cortical hyperostosis) is an uncommon benign and self limited disorder of unknown etiology, affecting the skeleton and its contiguous fasciae and muscles. Its occurrence in isolated cases or in multiple members in families suggests the existence of two different forms, namely a sporadic form and a familial form. The tibia is the predominant bone known to be affected in the familial form, while the mandible is mostly affected in the sporadic form. This benign and self-limited disorder has rarely late recurrence or persistence of symptoms with deformity. The patient in this case had immediate and complete resolution of her symptoms while receiving acetaminophen with no recurrent bone formation during treatment with antiinflammatory drugs. We describe sporadic, nonfamilial Caffey`s disease, affecting both radii and tibiae, but not involving the mandibular in a 4-month-old female infant.
Key Words: Caffey`s disease, Infantile cortical hyperostosis, Sporadic, Familial


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