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Whole Blood and Plasma Vitamin C Concentrations in Children of 1-6 Years of Age in the Chinju Area

Journal of the Korean Pediatric Society 2001;44(5):501-508.
Published online May 15, 2001.
Whole Blood and Plasma Vitamin C Concentrations in Children of 1-6 Years of Age in the Chinju Area
Hyang-Ok Woo1, Jin-Su Jun1, Ji-Hoe Park1, Young-Suk Kim1, Eun-A Kim1, Jae-Young Lim1, Myoung-Bum Choi1, Chan-Hoo Park1, Hee-Shang Youn1, Gyung-Hyuck Ko2, Chan-Hoo Park3, Woo-Kon Lee3, Myung-Je Cho3, Kwang-Ho Rhee3
1Departments of Pediatrics, Gyeongsang National University College of Medicine, Chinju, Korea
2Departments of Pathology, Gyeongsang National University College of Medicine, Chinju, Korea
3Departments of Microbiology, Gyeongsang National University College of Medicine, Chinju, Korea
진주지역에 거주하는 1-6세 소아의 전혈 및 혈장 비타민 C 농도
우향옥1, 전진수1, 박지희1, 김용숙1, 김은아1, 임재명1, 최명범1, 박찬후1, 윤희상1, 고경혁2, 백승철3, 이우곤3, 조명제3, 이광호3
1경상대학교 의과대학 소아과학교실
2경상대학교 의과대학 조직병리학교실
3경상대학교 의과대학 미생물학교실
Correspondence: 
Hee-Shang Youn, Email: hsyoun@nongae.gsnu.ac.kr
Abstract
Purpose
: Vitamin C among antioxidants in human is a physiological antioxidant for protection against diseases. We measured the vitamin C concentrations of whole blood and plasma among children in early childhood at normal condition in order to know the presence of vitamin C deficiency.
Methods
: The venous blood was collected from 471 subjects at 1-6 years of ages in Chinju. Concentra- tions of vitamin C in whole blood and plasma were measured by the 2,4-dinitrophenylhydrazine method.
Results
: Concentrations of vitamin C in whole blood and plasma were 1.68mg/dL and 0.94mg/dL, respectively. While concentrations of vitamin C in the whole blood and plasma of males were 1.69 mg/dL and 0.92mg/dL, respectively. Those of females, were 1.68mg/dL and 1.00mg/dL, respectively. The concentrations did not significantly differ by gender. Concentrations of vitamin C in plasma were positively correlated with the age of the entire study group and of female(P=0.01). Percentages of subjects with vitamin C concentrations of the whole blood less than 1.0mg/dL were 1.9%, and those of the plasma of below 0.6mg/dL were 20.6%.
Conclusion
: Concentrations of vitamin C in whole blood and plasma did not show normal distribution. And there were no relationship among age, gender, and vitamin C concentrations at early childhood. A significant number of children in Chinju had suboptimal plasma vitamin C concentration. These findings suggest a need for an increased vitamin C intake in this area.
Key Words: Whole blood, Plasma, Vitamin C, Antioxidant, Child


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