| Two Cases of Disseminated Intravascular Coagulation Due to Status Epilepticus with High Fever |
|
Song Heui Shin, Kyung-Rye Moon, Eun-Young Kim, Young-Il Rho |
|
Department of Pediatrics, College of Medicine, Chosun University, Gwangju, Korea |
| 고열로 인한 간질중첩증 환아에서 발생한 범발성 혈관내 응고 증후군 2례 |
|
신송희, 문경래, 김은영, 노영일 |
|
조선대학교 의과대학 소아과학교실 |
|
|
|
|
| Abstract |
|
Status epilepticus has been occasionally reported as a cause of acute disseminated intravascular
coagulation(DIC), but little is known regarding the pathogenesis of this uncommon association.
The occurrence of DIC in status epilepticus may be related to widespread endothelial damage
secondary to seizure-induced hyperpyrexia or status epilepticus due to high fever. We experienced
two cases of status epilepticus accompanying fever in which laboratory data demonstrated activation
of coagulation and fibrinolytic systems in a 3-year-old girl and a 12-month-old boy. There
was no evidence of infection, trauma, brain damage, or toxic ingestion as alternative explanations
for the consumptive coagulopathy. Hematologic parameters did not improve despite multiple
transfusions of red blood cells, pletelets, and fresh frozen plasma. Body temperature should be
monitored closely in patients with status epilepticus and efforts directed toward prompt lowering
of body temperature to prevent the development of consumption coagulopathy. |
| Key Words:
Disseminated intravascular coagulation(DIC), Status epilepticus, Fever |
|
PDF Links
Download Citation
