Journal of the Korean Pediatric Society 1982;25(7):730-736.
Published online July 31, 1982.
Disseminated Intravascular Coagulation in an Infant Born after Abruptio Placentae.
Soon Ung Kang, Jung Hwan Choi, E Boong Kwon, Chong Ku Yun, Kwang Wook Ko, Je G Chi, Chul Woo Kim
1Dept. of Pediatrics, College of Medicine, Seoul National University, Korea.
2Dept. of Pathology, College of Medicine, Seoul National University, Korea.
태반조기 박리 후 출생한 신생아의 파종성 혈관내 응고병 증 1 례
강순응, 최중환, 권이붕, 윤종구, 고광욱, 지제근, 김철우
1서울대학교 의과대학 소아과학교실
2서울대학교 의과대학 병리학교실
Premature separation of the placenta(abruptio placentae), as a serious obstetric complication, has been recognized to be associated with disseminated intravascular coagulation(DIC) in the newborn period. However, pathologic evidence for DIC generally has been lacking or rarely reported. Recently we have experienced one case of DIC in an infant born after abruptio placentae. The infant had suffered from cyanosis, dyspnea and convulsion. The peripheral blood smear of this infant revealed severe thrombocytopenia, but there was no evidence of external bleeding. At autopsy widespread hyaline thrombi were observed in the small vessels and capillaries of the brain and liver. The brain showed diffuse cortical and subcortical white matter necrosis associated with hemorrhage. Bilateral symmetrical necrosis of the thalamus was also seen. Massive fresh hemorrhage was present in the endometrium and myometrium. We considered tha tthe above findings were consistent with DIC. Pertinent literatures on neonatal DIC are also reviewed briefly.
Key Words: Disseminated intravascular coagulation(DIC), Abruptio placentae

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