| Diagnostic Utility of D-dimer Test in Disseminated Intravascular Coagulation with Sepsis |
|
Jung Eun Kim, Young Mi Hong, Gyung Hee Kim |
|
Department of Pediatrics, College of Medicine, Ewha Womans University, Seoul, Korea |
| 패혈증과 동반된 범발성 혈관내 응고장애의 진단에 있어서 D-dimer의 유용성 |
|
김정은, 홍영미, 김경희 |
|
이화여자대학교 의과대학 소아과학교실 |
|
|
|
|
| Abstract |
Purpose
: Disseminated intravascular coagulation(DIC) is a confusing disorder from both a diagnostic and therapeutic standpoint.
In order to investigate the effectiveness of D-dimer test in disseminated intravascular coagulation associated with sepsis, D-dimer level and other laboratory tests were performed.
Methods
: Fifty patients with disseminated intravascular coagulation associated with sepsis, who were admitted to the department of pediatrics, were evaluated by several tests(total WBC, erythrocyte sedimentation rate, C-reactive protein, blood culture test, prothrombin time, partial thromboplastin time, fibrinogen, fibrin degradation product, and D-dimer). If the test showed abnormal, follow-up study was performed.
Results
: The positive rate of D-dimer in DIC was 72% and FDP 58%. The false positive rate of D-dimer level in normal children was 3.3% and FDP 6.7%. There was a significant linear correlation between D-dimer and FDP.
Conclusion
: D-dimer test was the most effective test for diagnosing disseminated intravascular coagulation. |
| Key Words:
Disseminated intravascular coagulation, D-dimer test |
|
PDF Links
Download Citation
