| Clinical Characteristics of Infant Kawasaki Disease |
|
Yeun Keun Choi1, Jung Min Hong1, Su Mi Ihn1, Hae Kyeung Lim2, Hong Ryang Kil3 |
1Department of P ediatrics, Daejeon Sun General Hospital, Daejeon, Korea
1Department of P ediatrics, Daejeon Sun General Hospital, Daejeon, Korea
2Department of Pediatrics, Daejeon Chungang Hospital, Daejeon, Korea
3Department of P ediatrics, College of Medicine, Chungnam National University, Daejeon, Korea |
| 영아기 가와사끼병의 임상 양상 |
|
최윤근1, 홍정민1, 인수미1, 임혜경2, 길홍량3 |
1대전선병원 소아과
1대전선병원 소아과
2대전중앙병원 소아과
3충남대학교 의과대학 소아과학교실 |
Correspondence:
Hong Ryang Kil, Email: gilhong@cnu.ac.kr
|
|
|
|
|
| Abstract |
Purpose
: To assess the incidence of coronary artery lesion(CAL) and the efficacy of intravenously
administered immune globulin(IVGG) and aspirin therapy, identify risk factors for CAL, and
analyze clinical characteristics in infants less than 12 months of age with Kawasaki disease.
Methods
: Retrospective chart review of children less than 12 months of age with Kawasaki disease
between 1994 and 1998, diagnosed at Chungnam National University Hospital.
Results
: Of 202 patients with Kawasaki disease, 32(16 percent) were less than 1 year of age, including
7(3 percent) less than 6 months. Sex ratio of male to female was 2.5 : 1. Age at onset
and Harada score were a predictor of the development of CAL : 5(71 percent) of 7 children less
than 6 months and 10(40 percent) of 25 children between 6 to 12 months of age acquired CAL
(P < 0.05), and 1(14 percent) of 7 children less than 6 months of age acquired giant CAL. No specific
clinical or laboratory features predicted the development of CAL. Persistent(greater than 1
year) CAL were present in 2(7 percent) of 29 IVGG-treated children. The typical clinical features
of Kawasaki disease was noted 24(75 percent) of 32 and the atypical one, 8(25 percent) of 32
children less than 12 months of age.
Conclusion
: Patients with Kawasaki disease of less than 12 months of age are at particularly increased
risk of having CAL and difficulty in diagnosis due to atypical clinical features. So, it is
suggested to intervene in the diagnostic criteria or risk factors for CAL, especially for patients with
infant Kawasaki disease of less than 6 months of age. |
| Key Words:
Infant Kawasaki disease, coronary artery lesion |
|
PDF Links
Download Citation
