| The Change of White Blood Cell Count Following
Transfusion in Preterm Neonates |
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Soo Young Yoon, Gum Joo Lee, Gui Young Jung |
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Department of Pediatrics, Bangjeege Hospital, Seoul, Korea |
| 미숙아에서 수혈 후 백혈구수의 변화 |
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윤수영, 이금주, 정귀영 |
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방지거병원 소아과 |
Correspondence:
Soo Young Yoon, Email: YSYSDY@medigate.net
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| Abstract |
Purpose
: We intended to find out how the red cell transfusion would change the white cell count in preterm neonates under treatment in the intensive care unit. We also speculated whether the magnitude of such a change could indicate a potential neonatal infection.
Methods
: Total white blood cell count, total neutrophil count, and band count were compared and analyzed retrospectively on 33 preterm neonates who received red cell transfusions in our hospital's intensive care unit over a period of two years and a month.
Results
: We found a mean change of 1.33?03/mm3 and 0.55?03/mm3 in total white blood cell count and total neutrophil count in the first eight hours following the red cell transfusion. No significant change was observed in band count between pre and post-red cell transfusion.
Conclusion
: A mild increase in the white blood cell count caused by an increase in neutrophil count was observed temporarily following the red cell transfusion. But the white blood cell count returned to the pre-transfusion level in about 24 hours, indicating that such a low level of increase cannot be interpreted as an infection of a preterm neonate. |
| Key Words:
Leukocytosis, Newborn, Sepsis, Transfusion |
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