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The Use of Quadruple Blood Bags Transfusion of Low Birth Weight Neonates

Journal of the Korean Pediatric Society 1999;42(8):1122-1129.
Published online August 15, 1999.
The Use of Quadruple Blood Bags Transfusion of Low Birth Weight Neonates
Sang Hoon Lee1, Jean Yoon1, Yang Park1, Sung Kyu Lee1, Hee Chung Kim2, Woo Sup Shim1
1Departments of Pediatrics, Sejong Hospital, Puchon, Korea
2Departments of Clinical Pathology, Sejong Hospital, Puchon, Korea
저체중 신생아에서 다낭 채혈백을 이용한 농축적혈구 수혈의 유용성
이상훈1, 윤진1, 박양1, 이성규1, 김희정2, 심우섭1
1부천세종병원 소아과
2부천세종병원 임상병리과
Correspondence: 
Sang Hoon Lee, Email: 1
Abstract
Purpose
: Low-birth-weight(LBW) neonates often need multiple transfusions during their neonatal period. The routine use of the 500ml mono-bag system in Korea, even in neonatal transfusions, results in a great waste of blood and exposes the neonate to multiple blood donors. To reduce the waste of blood and the number of exposures, we used quadruple blood bags in the transfusion of LBW neonates.
Methods
: From November 1995 to April 1997, 86 neonates weighing less than 2,000gm were enrolled in this study. Forty-four of those neonates needed blood transfusions. Using quadruple blood bags, we were able to safely make 3 units of packed red blood cell(RBC) from each directed donors.
Results
: Seventy-seven units of packed RBC could be made from 29 directed donors and 58 of those units were actually transfused to the 25 neonates. Blood age of the directed donor blood prepared in the quadruple blood bags were relatively older than those of bank bloods at the time of transfusion, thus, K+ concentration was higher but the total K+ amounts infused through transfusions were within tolerable ranges in both groups.
Conclusion
: Using quadruple blood bag in the transfusion of LBW neonates, we could reduce the number of donor exposures and also the waste of blood. K+ loads to the neonates through the transfusion of directed donor blood were within tolerable range in the neonatal physiology.
Key Words: Transfusion, Directed donor blood, Quadruple blood bags


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