The Case of Persistent Pulmonary Hypertension of the New born. |
Sung Oh Kim, Soo Yup Lee, Kyoo Hwan Lee, Soo Jee Moon |
Department of Pediatrics, College of Medicine, Hanyang University, Seoul, Korea |
신생아 지속성 폐동맥 고혈압증 2례 |
김성오, 이수엽, 이규환, 문수지 |
한양대학교 의과대학 소아과학교실 |
Received: 28 July 1987 |
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Abstract |
Persistent pulmoanry hypertension of the newborn (PPHN) is a syndrome consisting of severe
hypoxemia and pulmoanry hypertension that appears within hours of birth.
The essential pathophysiologic features of this syndrome is pulmonary artery hypertension causing
right-to-left shunt through the patent ductus arteriosus or foramen ovale or both and clinically
manifested by central cyanosis and respiratory distress.
We recently have experienced 20 hour old female and 7 hour old male babies presented with
cyanosis and respiratory distress soon after birth.
Each case had evidence of pulmonary artery hypertension with right-to-left shunt, by both clinical
examination and echocardiography.
The 20 hour old female was suggested the primary type of PPHN, contrast echocardiogram showed
right-to-left shunt through the foramen ovale and finally improved to dischage without complication.
The other was thought the secondary type of PPHN due to meconium aspiration syndrome and the
autopsy findings were consistent with intra-acinar pulmonary arterial muscularization, probably
resulting from intrauterine hypoxia.
A brief review of related literatures is given. |
Key Words:
Persistent pulmonary hypertension of the newborn |
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