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Original Article
Infection
Clinical characteristics of pediatric patients infected with SARS-CoV-2 versus common human coronaviruses: a national multicenter study
In Suk Sol, Eun Lee, Hyeon-Jong Yang, Yong Ju Lee, Hye Yung Yum, Mi-Hee Lee, Mi Ae Chu, Hui Jeong Moon, Hyo-Bin Kim, Ju Hee Seo, Jung Yeon Shim, Ji Young Ahn, Yoon Young Jang, Hai Lee Chung, Eun Hee Chung, Kyunghoon Kim, Bong-Seong Kim, Cheol Hong Kim, Yang Park, Meeyong Shin, Kyung Suk Lee, Man Yong Han, Soo-Jong Hong, Eun Kyeong Kang, Chang Keun Kim; on behalf of The Pneumonia & Respiratory Disease Study Group of Korean Academy of Pediatric Allergy and Respiratory Disease
Clin Exp Pediatr. 2023;66(3):134-141.   Published online December 22, 2022
Question: The clinical differences between severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and human coronaviruses (HCoV) in children remain unknown.
Finding: This study compared the clinical findings of children infected with SARS-CoV-2 versus HCoV. Its findings suggest that children and adolescents with SARS-CoV-2 have a milder clinical course than those with HCoV.
Meaning: The clinical course of children and adolescents with SARS-CoV-2 should be closely monitored during the coronavirus disease 2019 pandemic.
Peripheral Blood Eosinophil Counts and Serum ECP in Adolescents with Long-term Asthma Remission and Persistent Bronchial Hyperresponsiveness : Comparison with Adolescents with Symptomatic Asthma
Hee Kang, Young Yoo, Jinho Yu, Yang Park, Young Yull Koh
Clin Exp Pediatr. 2003;46(10):1013-1018.   Published online October 15, 2003
Purpose : Bronchial hyperresponsiveness(BHR) in asthma is thought to be a consequence of underlying airway inflammation. But the mechanism responsible for persistent BHR in adolescents with long-term asthma remission is poorly understood. The aim of this study was to examine whether BHR in adolescents with asthma remission is associated with peripheral blood eosinophilia and/or increased serum levels of eosinophil cationic...
Exhaled Nitric Oxide Concentration in Children with Asthma and Allergic Rhinitis : Association with Atopy and Bronchial Hyperresponsiveness
Kyu Min Nah, Yang Park, Eun Kyeong Kang, Hee Kang, Young Yull Koh, Sun Wha Lee, Domyung Paek
Clin Exp Pediatr. 2003;46(3):284-290.   Published online March 15, 2003
Purpose : A new airway inflammatory marker, exhaled nitric oxide(ENO) has been reported to correlate with bronchial hyperresponsiveness(BHR) and atopy. The purpose of this study was to analyze the relationship of ENO with BHR or atopy in patients with asthma and with allergic rhinitis. Methods : The subjects consisted of 55 children with asthma, 17 with allergic rhinitis, and 14 healthy...
Blood Eosinophil and Serum Eosinophil Cationic Protein as a Marker of Bronchial Hyperresponsiveness in Children with Suspected Asthma
Yang Park, Hee Kang, Eun Kyeong Kang, Young Yull Koh
Clin Exp Pediatr. 2002;45(12):1577-1584.   Published online December 15, 2002
Purpose : Airway inflammation is considered to be a characteristic feature of asthma, and eosinophils are recognized as the most important inflammatory cells. This study aims to assess the importance of blood eosinophil count and serum eosinophil cationic protein(ECP) levels as a non- invasive marker of bronchial hyperresponsiveness(BHR) in children with suspected asthma. Methods : This study used data from 87...
Comparison of Eosinophil Markers between Acute and Recovery Stages in Children with Mycoplasma pneumoniae Pneumonia
Kyu Min Nah, Eun Kyeong Kang, Hee Kang, Yang Park, Young Yull Koh
Clin Exp Pediatr. 2002;45(10):1227-1233.   Published online October 15, 2002
Purpose : Several studies have shown that increases of eosinophil markers are common findings of asthma and Mycoplasma pneumoniae infection, and eosinophil markers reflect the clinical stage of asthma. The purpose of this study was to investigate the change of eosinophil markers according to the clinical stage of Mycoplasma pneumonia. Methods : The patient group consisted of 33 outpatient children with Mycoplasma pneumonia. Peripheral blood...
Age-related Results of Skin Prick Test in Children with Allergic Asthma
Jae Sung Son, Yang Park, Yong Han Sun, Myung Hyun Lee, Young Yull Koh
Clin Exp Pediatr. 2001;44(2):193-199.   Published online February 15, 2001
Purpose : Skin reactivity to different allergens may vary with age, since the degree and type of sensitization may be related not only to genetic factors but also to the intensity and duration of exposure to the allergens. The aim of this study was to evaluate profile of sensitization to airborne allergens according to age in children with allergic asthma. Methods...
High-Resolution Computed Tomography(HRCT) Findings of the Lung in Asthmatic Children and Their Correlation with Clinical Characteristics
Do Kyun Kim, Yang Park, Young Yull Koh, Jung Eun Chun, Woo Sun Kim
Clin Exp Pediatr. 2000;43(12):1583-1590.   Published online December 15, 2000
Purpose : The purposes of this study were to determine the abnormal high-resolution computed tomography(HRCT) findings of the lung in uncomplicated asthmatic children, to compare the clinical characteristics between normal and abnormal HRCT finding groups and to correlate abnormal HRCT findings with clinical characteristics, especially FEV1 and PC20. Methods : Forty asthmatic children were studied. Inspiratory and expiratory HRCT scans were...
The Use of Quadruple Blood Bags Transfusion of Low Birth Weight Neonates
Sang Hoon Lee, Jean Yoon, Yang Park, Sung Kyu Lee, Hee Chung Kim, Woo Sup Shim
Clin Exp Pediatr. 1999;42(8):1122-1129.   Published online August 15, 1999
Purpose : Low-birth-weight(LBW) neonates often need multiple transfusions during their neonatal period. The routine use of the 500ml mono-bag system in Korea, even in neonatal transfusions, results in a great waste of blood and exposes the neonate to multiple blood donors. To reduce the waste of blood and the number of exposures, we used quadruple blood bags in the transfusion...
Balloon Valvuloplasty of Pulmonary Stenosis in Patients Younger than 6 Months of Age
Yang Park, Do Jun Cho, Woo Sub Sim, In Seung Park, Eun Jung Bae, Seong Ho Kim
Clin Exp Pediatr. 1999;42(5):631-636.   Published online May 15, 1999
Purpose : Balloon valvuloplasty(BVP) is the treatment of choice for valvular pulmonary stenosis (PS). However, this procedure was usually performed in children older than 2 years. The purpose of the present study was to assess the safety and efficacy of BVP in young infants. Methods : Retrospective analysis of the medical records of 25 infants younger than 6 months of age...
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