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Two Cases of Wolff-Parkinson-White Syndrome in a Family

Journal of the Korean Pediatric Society 2002;45(9):1150-1154.
Published online September 15, 2002.
Two Cases of Wolff-Parkinson-White Syndrome in a Family
Chan Uhng Joo, So Hee Lim, Pyung Han Hwang
Department of Pediatrics, Medical School, Chonbuk National University, Institute of Cardiovascular Research, Jeonju, Korea
가족 내 발생을 보인 Wolff-Parkinson-White 증후군 2례
주찬웅, 임소희, 황평한
전북대학교 의과대학 소아과학교실, 심혈관연구소
Correspondence: 
Chan Uhng Joo, Email: joocu@moak.chonbuk.ac.kr
Abstract
Wolff-Parkinson-White(WPW) syndrome is characterized by electrographic evidence of ventricular preexcitation, which predisposes to supraventicular arrhythmias. Familial occurrence of WPW syndrome is uncommon. We observed two affected siblings in a family. Five members of the family underwent 12-lead electrocardiography and echocardiography. Although known genetic abnormality of the 7q34-q36(PRKAG2) for the familial WPW syndrome was evaluated, the mutation was not detected in this family. Other unknown mutations responsible for this familial WPW syndrome were suggested.
Key Words: Wolff-Parkinson-White syndrome, Family


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