Two Cases of Wolff-Parkinson-White Syndrome in a Family |
Chan Uhng Joo, So Hee Lim, Pyung Han Hwang |
Department of Pediatrics, Medical School, Chonbuk National University, Institute of Cardiovascular Research, Jeonju, Korea |
가족 내 발생을 보인 Wolff-Parkinson-White 증후군 2례 |
주찬웅, 임소희, 황평한 |
전북대학교 의과대학 소아과학교실, 심혈관연구소 |
Correspondence:
Chan Uhng Joo, Email: joocu@moak.chonbuk.ac.kr |
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Abstract |
Wolff-Parkinson-White(WPW) syndrome is characterized by electrographic evidence of ventricular preexcitation, which predisposes to supraventicular arrhythmias. Familial occurrence of WPW syndrome is uncommon. We observed two affected siblings in a family. Five members of the family underwent 12-lead electrocardiography and echocardiography. Although known genetic abnormality of the 7q34-q36(PRKAG2) for the familial WPW syndrome was evaluated, the mutation was not detected in this family. Other unknown mutations responsible for this familial WPW syndrome were suggested. |
Key Words:
Wolff-Parkinson-White syndrome, Family |
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