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A Case of Diffuse Panbronchiolitis Developing in Childhood

Korean Journal of Pediatrics 2005;48(1):97-100.
Published online January 15, 2005.
A Case of Diffuse Panbronchiolitis Developing in Childhood
Jung Hoon You, Hyung Shin Lee, Kyung Yil Lee, Ja Hyun Hong, Mi Hee Lee, Byung Cheol Lee
Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea
소아에서 발생한 미만성 범세기관지염 1례
유정훈, 이형신, 이경일, 홍자현, 이미희, 이병철
가톨릭대학교 의과대학 소아과학교실
Correspondence: 
Hyung Shin Lee, Email: leehs3@catho; ic.ac.kr
Abstract
Diffuse panbronchiolitis(DPB) is a chronic inflammatory airway disease predominantly affecting respiratory bronchioles, with distinct clinicopathological profiles. It was first described in 1966 by Yamanaka et al. The etiology of DPB is not yet clear, and the natural history of the disease is respiratory failure leading to cor pulmonale and ultimately death. But the long-term use of low-dose macrolide has proven to be highly effective in treating patients with DPB. Usual age at diagnosis is over 40. A few cases of DPB have been reported in Korea since 1992 but there have been no reports in children. We experienced a case of DPB in a 12-year-old girl. Therefore, we report the case with a brief review of the related literature.
Key Words: Diffuse panbronchiolitis , Children


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