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Clinical Entities and Etiology of Invasive Bacterial Infections in Apparently Healthy Children

Korean Journal of Pediatrics 2005;48(11):1193-1200.
Published online November 15, 2005.
Clinical Entities and Etiology of Invasive Bacterial Infections in Apparently Healthy Children
Joon Ho Lee1, Eun Kyoung Song1, Jin A Lee1, Nam Hee Kim1, Dong Ho Kim2, Ki Won Park3, Eun Hwa Choi1, Hoan Jong Lee1
1Department of Pediatrics, Seoul National University College of Medicine
2Cancer Center Hospital, Seoul, Korea
3National Police Hospital, Seoul, Korea
기저 질환이 없는 소아에서 발생한 침습성 세균 감염의 임상 양상과 원인균
이준호1, 송은경1, 이진아1, 김남희1, 김동호2, 박기원3, 최은화1, 이환종1
1서울대학교 의과대학 소아과학교실
2국립원자력병원
3국립경찰병원
Correspondence: 
Hoan Jong Lee, Email: hoanlee@snu.ac.kr
Abstract
ilus influenzae has been declined to 4% each from 23% and 14%, respectively, compared to previous study. S. agalactiae was the most common isolate in the infants ≤3 months. Among the infants and children aged 3 months to 2 years and children of 2-5 years, S. pneumoniae(57%, 52%, respectively, in each group) was the most common isolates followed by S. aureus(17% and 24%, respectively). S. aureus was the most common isolates(73%) in children >5 years. Primary bacteremia was the most common clinical diagnosis(27%). S. pneumoniae was responsible for 42% of primary bacteremia, 50% of meningitis, and 69% of bacteremic pneumonia and empyema. S. aureus accounted for 80% of bone and joint infections. The case fatality rate was 8.1% for all invasive infections.
Conclusion
: We reviewed frequency of bacterial agents of invasive infections in children. The data may be useful for pediatricians to select adequate empirical antibiotics in the management of invasive bacterial infections.
Key Words: Bacterial infections , Bacteremia , Meningitis , Streptococcus pneumoniae , Staphylococcus aureus


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