| Clinical Entities and Etiology of Invasive Bacterial Infections in Apparently Healthy Children |
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Joon Ho Lee1, Eun Kyoung Song1, Jin A Lee1, Nam Hee Kim1, Dong Ho Kim2, Ki Won Park3, Eun Hwa Choi1, Hoan Jong Lee1 |
1Department of Pediatrics, Seoul National University College of Medicine
2Cancer Center Hospital, Seoul, Korea
3National Police Hospital, Seoul, Korea |
| 기저 질환이 없는 소아에서 발생한 침습성 세균 감염의 임상 양상과 원인균 |
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이준호1, 송은경1, 이진아1, 김남희1, 김동호2, 박기원3, 최은화1, 이환종1 |
1서울대학교 의과대학 소아과학교실
2국립원자력병원
3국립경찰병원 |
Correspondence:
Hoan Jong Lee, Email: hoanlee@snu.ac.kr
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| Abstract |
ilus influenzae has been declined to 4% each from 23% and 14%, respectively, compared to previous study. S. agalactiae was the most common isolate in the infants ≤3 months. Among the infants and children aged 3 months to 2 years and children of 2-5 years, S. pneumoniae(57%, 52%, respectively, in each group) was the most common isolates followed by S. aureus(17% and 24%, respectively). S. aureus was the most common isolates(73%) in children >5 years. Primary bacteremia was the most common clinical diagnosis(27%). S. pneumoniae was responsible for 42% of primary bacteremia, 50% of meningitis, and 69% of bacteremic pneumonia and empyema. S. aureus accounted for 80% of bone and joint infections. The case fatality rate was 8.1% for all invasive infections.
Conclusion
: We reviewed frequency of bacterial agents of invasive infections in children. The data may be useful for pediatricians to select adequate empirical antibiotics in the management of invasive bacterial infections. |
| Key Words:
Bacterial infections , Bacteremia , Meningitis , Streptococcus pneumoniae , Staphylococcus aureus |
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