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Catch-up growth and development of very low birth weight infants

Korean Journal of Pediatrics 2006;49(1):29-33.
Published online January 15, 2006.
Catch-up growth and development of very low birth weight infants
Tae Ho Ma, Kyung Ah Kim, Sun Young Ko, Yeon Kyung Lee, Son Moon Shin
Department of Pediatrics, College of Medicine, Samsung Cheil Hospital, Sungkyunkwan University, Seoul, Korea
극소저출생체중아의 따라잡기 성장 및 발달평가
마태호, 김경아, 고선영, 이연경, 신손문
성균관대학교 의과대학 삼성제일병원 소아과
Correspondence: 
Yeon Kyung Lee, Email: ykleeped@hanmail.net
Abstract
Purpose
: The aim of this study was to analyze the results and contributing factors of catch-up growth in very low birth weight infants(VLBWI) at the corrected age of 2 years. In addition, we looked for a relationship between the catch-up growth and the development by the bayley scales of infant development II(BSID II).
Methods
: A retrospective analysis by evaluating medical records was done for the 76 VLBWI whose follow-up was possible up to a corrected age of 2 years, out of the 114 who had been treated in the neonatal intensive care unit during the January of 2000 to December of 2001 at Samsung Cheil Hospital. Based on the Standard Korean Infant's Growth Curve, the catch-up growth group was defined over the 10th percentile of weight at 2 years as the corrected age and the failed catch-up growth group was defined under the 10th percentile. We investigated the clinical factors and courses of each group and compared the scores of the BSID II.
Results
: The catch-up growth group of the VLBWI was 51 infants and the failed catch-up growth group was 25 infants. In comparison with maternal clinical factors, use of antenatal steroids was significantly higher in the catch-up growth group. In comparisn with clinical factors and courses of VLBWI, two clinical factors were significantly different between the two groups : birth weight and intrauterine growth retardation(IUGR). Numbers of delayed development were increased in the failed catch-up growth group but statistically significant differences could not be observed.
Conclusion
: The catch-up growth of the VLBWI was affected by the use of antenatal steroids, birth weight and IUGR. No significant differences regarding neurodevelopmental outcome were observed between the catch-up and failed catch-up growth groups.
Key Words: Very low birth weight infant , Catch-up growth , Bayley scales of infant development II


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