| A clinical study of child bacterial meningitis in Daejeon and Chungcheong area : 2001-2005 |
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Yong Joo Lee1, Soo Jin Lee1, Ho Jin Park1, Young Hyuk Lee2, So Young Kang3, Young Chang Kim4, In Kyu Lee4, Kyung Yeon Lee5, Keon Su Lee6, Won Seop Kim7 |
1Department of Pediatrics, Eulji University School of Medicine
2Department of Pediatrics Konyang University College of Medicine
3Department of Pediatrics, Dankook University College of Medicine, Cheonan
4Department of Pediatrics, Soonchunhyang University College of Medicine, Cheonan
5Department of Pediatrics, The Gatholic University College of Medicine, Chongju
6Department of Pediatrics, Chungnam National University College of Medicine
7Department of Pediatrics, Chungbuk National University College of Medicine, Korea |
| 대전·충청 지역의 소아 세균성 수막염에 대한 임상적 연구 : 2001-2005 |
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이용주1, 이수진1, 박호진1, 이영혁2, 강소영3, 김영창4, 이인규4, 이경연5, 이건수6, 김원섭7 |
1을지의과대학교 소아과학교실
2건양대학교병원 소아과학교실
3단국의대 천안병원 소아과학교실
4순천향의대 천안병원 소아과학교실
5청주성모병원 소아과학교실
6충남대학교병원 소아과학교실
7충북대학교병원 소아과학교실 |
Correspondence:
Ho Jin Park, Email: phojin71@hanmail.net
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| Abstract |
Purpose
: The purpose of this study was to analyze the epidemiology, causative organism, clinical manifestation and prognosis of bacterial meningitis for children after the introduction of Haemophilus influenzae type b (Hib) vaccine in Daejeon and Chungcheong area.
Methods
: We analyzed retrospectively 53 medical records who had been diagnosed with bacterial meningitis at 10 general or university hospitals in Daejeon and Chungcheong area. All patients aged 1 month-14 years admitted between January 2001 through December 2005.
Results
: During the 5-year study period, 40 of all cases were positive for bacterial growth. Of the 40 cases that were CSF culture-proven bacterial meningitis, Streptococcus peumoniae was the most common bacteria for 17 (32.1%) of all cases, followed by H. influenzae for 10 (18.9%), Neisseria meningitidis for 3 (5.7%). In this study, the most common clinical manifestation is fever, accompanied by all cases. CSF leukocyte count was more than 100/mm3 in 45 (84.1%) cases. CSF glucose concentration was less than 50 mg/dL in 42 (79.2%) cases and protein concentration was more than 45 mg/ dL in 49 (92.5%) cases. 45 of all cases made a recovery after treatment and were discharged. Most common complication after treatment is subdural effusion (19.0%) and hearing disturbance (9.4%).
Conclusion
: The most common organism of culture-proven bacterial meningitis in the children beyond neonatal period was S. pneumoniae. Continued surveillance studies were demanded to know the altered incidence of bacterial meningitis, because we expect the incidence of S. pneumoniae meninigitis will be on the decrease after more active innoculation of pneumococcal protein conjugate vaccine. |
| Key Words:
Meningitis , Bacterial , Child , Streptococcus pneumoniae , Haemophilus influenzae |
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