| A case of dapsone syndrome |
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Yoo Jong Won, Ok Lan Kim, Seung Taek Yu, Young Wook Yoon, Du Young Choi |
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Department of Pediatrics, School of Medicine, Wonkwang University, Iksan, Korea |
| Dapson 증후군 1례 |
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원유종, 김옥란, 유승택, 윤영욱, 최두영 |
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원광대학교 의과대학 소아과학교실 |
Correspondence:
Du Young Choi, Email: cdy8118@wonkwang.ac.kr
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| Abstract |
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Diamino-diphenyl-sulfone (Dapsone) is widely used in the treatment of leprosy and a variety of blistering skin diseases. It sometimes has adverse side effects with common usual doses, such as skin, nervous system, gastrointestinal tract, liver, kidney and hematologic toxicity. One of these side effects is a rare but serious hypersensitivity reaction called dapsone syndrome, which occurs several weeks after the initial administration of the drug and results in unpredictable, sometimes fatal outcomes. This report deals with a 13-year-old girl's case with typical features of dapsone syndrome that included fever, exfoliative dermatitis, jaundice, hemolytic anemia and pleural effusion after being treated with dapsone for four weeks. |
| Key Words:
Dapsone syndrome, Hemolytic anemia |
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