Autoimmune hepatitis and thyroiditis associated with
antituberculous medications : A case report |
Seong Keun Yu1, Sara Kim1, Jin Soo Moon1, Han Seong Kim2 |
1Department of Pediatrics, Inje University Ilsan Paik Hospital, Goyang, Korea 2Department of Pathology, Inje University Ilsan Paik Hospital, Goyang, Korea |
항결핵약으로 유발되고 갑상선염이 동반된자가면역간염 1례 |
유성근1, 김사라1, 문진수1, 김한성2 |
1인제대학교 의과대학 소아과학교실 2인제대학교 의과대학 병리과교실 |
Correspondence:
Jin Soo Moon, Email: jsmoon@ilsanpaik.ac.kr |
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Abstract |
Drug-induced toxic hepatitis is a relatively common hepatic disease in children, and it is usually self-limiting upon cessation of the offending drugs. Antituberculous drugs are well known for inducing hepatitis. Some cases of drug-induced hepatitis with autoimmune features have been reported; in these cases, the offending drugs were usually methyldopa, nitrofurantoin, minocycline, and interferon. The authors report the first case in Korea of drug-induced autoimmune hepatitis associated with thyroiditis and multiple autoantibodies that was induced by the antituberculous drugs isoniazid and rifampin. |
Key Words:
Toxic hepatitis, Autoimmune thyroiditis, Isoniazid, Rifampin |
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