| Relationship between iron deficiency anemia and febrile convulsion in infants |
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Youn Soo Jun1, Ho Il Bang1, Seung Taek Yu1, Sae Ron Shin2, Du Young Choi1 |
1Department of Pediatrics, Wonkwang University School of Medicine, Iksan, Korea
2Department of Family Medicine, Wonkwang University School of Medicine, Iksan, Korea |
| 영아에서 철결핍 빈혈과 열성경련과의 상관관계 |
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전윤수1, 방호일1, 유승택1, 신새론2, 최두영1 |
1원광대학교 의과대학 소아과학교실
2원광대학교 의과대학 가정의학과교실 |
Correspondence:
Du Young Choi, Email: cdy8118@wonkwang.ac.kr
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Received: 1 December 2009 • Revised: 18 February 2010 • Accepted: 10 March 2010 |
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| Abstract |
Purpose
: The association between iron deficiency anemia and febrile convulsion in infants has been examined in several studies with conflicting results. Therefore, the authors aimed to evaluate the precise relationship involved.
Methods
: In this case-control study, the authors assessed 100 children with a diagnosis of febrile convulsion, aged between 9 months and 2 years, during January 2007 to July 2009. The control group consisted of 100 febrile children without convulsion; controls were closely matched to the cases by age, gender, and underlying disease.
Results
: The mean ages of the febrile convulsion and control group were 16.3¡¾7.4 and 15.8¡¾6.1 months, respectively, and the two groups had no differences in clinical features. Iron deficiency anemia (Hb <10.5 gm/dL) was more frequent in the febrile convulsion group than in the control group, although there was no statistical significance. Unexpectably, the RDW (red blood cell distribution width) was significantly lower and the MCNC (mean corpuscular hemoglobin concentration) was significantly higher among seizure cases than among the controls (P<0.05). There is no statistical difference between simple and complex febrile groups in the clinical and laboratory profiles. On multiple logistic regression analysis, iron deficiency anemia was more frequent, but the RDW was lower, among the cases with febrile convulsion, compared with the controls.
Conclusions
: Our study suggests that the iron deficiency anemia is associated with febrile convulsion, and screening for iron deficiency anemia should be considered in children with febrile convulsions. |
| Key Words:
Febrile convulsion, Iron deficiency anemia |
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