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A case of neonatal systemic candidiasis.

Journal of the Korean Pediatric Society 1991;34(9):1286-1293.
Published online September 30, 1991.
A case of neonatal systemic candidiasis.
Eun Ae Park, Gyoung Hee Kim
Department of Pediatrics, College of Medicine, Ewha Womans University, Seoul, Korea
신생아 전신성 칸디다증 1례
박은애, 김경희
이화여자대학교 의과대학 소아과학교실
Received: 7 May 1991   • Accepted: 24 June 1991
Systemic infection with Candida albicans in very premature infants is frequently fatal or associated with significant morbidity in survivors. Several common practices in newborn intensive care units, such as insertion of indwelling catheters, provision of parenteral nutrition, and prolonged administra- tion of broad-spectrum antibiotics or aminophylline, are associated with an increased risk of systemic disease. We have experienced a case of systemic candidiasis in 1/365 year old male newborn with mechani- cal ventilation for RDS. He had a tracheal intubation and umbilical artery catheterization and was treated with aminophylline, antibiotics and hyperalimentation. About 20 days after treatment, fungus was isolated in urine by suprapubic punctured, blood, tracheal secretion, gastric content and ear discharge. Abdominal ultrasonography showed multiple fungus ball in both kidney. Amphotericin B and 5-Flucytosine were administered under the impression of systemic candidiasis. We had an excellent results with resolution of fungus ball in renal ultrasonography after treatment.
Key Words: Systemic candidiasis, Fungus ball, Premature infants

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