| A case of Addison's disease. |
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Cheol Hee Hwang, Dong Kui Lee, Myung Sug Nam, Mun Ki Cho |
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Department of Pediatrics, St. Columban Hospital, Mokpo, Korea |
| 소아 Addison병 1례 |
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황철희, 이동규, 남명숙, 조문기 |
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성골롬반병원 소아과 |
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Received: 27 November 1990 • Accepted: 13 March 1991 |
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| Abstract |
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Addison’s disease is a rare disorder resulting from progressive adrenocortical destruction regardless
of the nature of underlying process.
A 5-year-old boy with Addison’s disease without other endocrine disorder presented with a brief
review of the literature. The patient was admitted to out hospital because of poor appetite and
generalized darkish brown pigmentation of skin and mucous membrane.
On physical examination, skin and mucous membrane were diffusely darkish brown, especially over
the face, finger tips, toe tips, lips and gingiva. Laboratory studies showed low serum cortisol, high
ACTH concentration and low 24 hours urinary 17-KS and 17-OHCS, but 8 hours intravenous ACTH
stimulation test failed to rise the plasma cortisol and 24 hours urinary 17-KS and 17-OHCS level.
The patient has been placing on cortisone acetate with improvement. |
| Key Words:
Addison's disease, Chronic adrenal insufficiency |
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