| Morphological study on the development of human fetal kidney. |
|
Hee Young Shin1, Kwang Wook Ko1, Je Geun Chi2 |
1Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea
2Department of Pathology, Seoul National University College of Medicine, Seoul, Korea |
| 사람의 신발달에 관한 형태학적 연구 |
|
신희영1, 고광욱1, 지제근2 |
1서울대학교 의과대학 소아과학교실
2서울대학교 의과대학 병리학교실 |
|
Received: 26 July 1991 • Accepted: 26 July 1991 |
|
|
| Abstract |
|
A total of 293 human fetal kidneys, including those of 42 embryos are studied for the elucidation
of temporal development of the kidney. These specimens were interpreted as normal by thorough
postmortem examinations. The age of the specimens was determined by developmental horizon
criteria in embryos and by correlating crown-rump length in fetuses. Embryos were embedded in toto,
cut in various planes and reconstructed after serial sections were made. Crown-rump length, body
weight, kidney weight and number of lobules were applied for establishing parameters of microscopic
findings such as cortical thickness, size of the glomerulus and presence or absence of nephrogenic
zone. By utilizing these data one could establish the index of maturity of the kidney development in
the fetus.
The kidney development could be summarized as follows:
Histological characteristics of the mesonephros and metanephros were delineated in time sequence
in embryos and morphological characteristics of the fetal kidneys were noted by 4 week interval.
Cortical thickness correlated linearly with gestational age until 32-week of gestation and absence of
nephrogenic zone could be considered as an index of maturity in the latter part of gestation. Number
of lobules and the size of the glomeruli correlated poorly with gestational age. |
| Key Words:
Kidney, Renal development, Morphology, Embryo, Fetus |
|
PDF Links
Download Citation
