Warning: fopen(/home/virtual/pediatrics/journal/upload/ip_log/ip_log_2024-05.txt) [function.fopen]: failed to open stream: Permission denied in /home/virtual/pediatrics/journal/ip_info/view_data.php on line 82

Warning: fwrite(): supplied argument is not a valid stream resource in /home/virtual/pediatrics/journal/ip_info/view_data.php on line 83
The clinical study on MCLS.

Journal of the Korean Pediatric Society 1991;34(2):240-249.
Published online February 28, 1991.
The clinical study on MCLS.
Young Sun Ko, Ji Sun Cho, Hong Bae Kim, Ji Sub Oh
Department of Pediatrics, Wallace Memorial Baptist Hospital, Pusan, Korea
MCLS에 관한 임상적 고찰
고영선, 조지선, 김홍배, 오지섭
왈레스기념 침례병원 소아과
Received: 9 July 1990   • Accepted: 26 September 1990
Forty six children with mucocutaneous lymph node syndrome were diagnosed and treated through admission at the Department of Pediatrics, Wallace Memorial Baptist Hospital from January 1987 to January 1990. Ther were investigated for clinical pattern and laboratory correlations. The results were as follows: 1) Most patients (95.7%) were under four years of the age. 2) The ratio of male to female was 1.6:1. 3) Seasonal incidence was high in February, June and July, respectively. 4) The incidence of principal symptoms were fever lasting 8.4±2.6 day (100%) bilateral conjun- ctival injection 995.7%), skin rash (91.3%), red fissured lips (82.6%), stawberay tongue (80.4%), desquamation (80.4%), cervical lymphadenopathy (52.2%), and induration of palm and sole (47.8%). The incidence of other symptons were cough and coryza (58.7%), vomiting (32.6%) diarrhea (34. 8%) & jaundice (13.0%). The associated diseases were one case of pericardial effusion, two cases of GB hydrops and seven cases of pneumonia. 5) The abnormal laboratory findings observed were anemia (19.6%), leukocytosis (97.8%) throm- bocytosis (91.3%), increases ESR (100%),positive CRP (100%), pyuria (50.0%), increased SGOT (31. 8%), increased SGPT (50.0%), increased LDH (37.2%),increased CPK (23.7%) & increased tz2globulin (87.1%). The peak thrombocytosis appeared on the 10-16 days after onset of the disease & returned to normalization on 16-24 days after onset of the disease. 6) The abnormal findings of EKG were found in 78.3% of the patients and were prolonged QTc interval (56.5%), low R wave in VI,6 (32.6%), ST-T wave change (26.0%), prolonged PR interval (6. 5%) and Flat T wave in V5, 6 (4.3%). 7) The M-mode echocardiographic abnormality consisted of increase in ratio of the left posterior wall to septal excursion in (4.3%), decrease of fractional shortening in (32.6%), increase of systolic time interval in (19.6%). The 2D echocardiographic abnormalities consisted of coronary aneurysm (23.9%), pericardial effusion (2.2%) & grade I /IV mitral regurgitation (10.9%). The sites of coro- nary aneurysm were left coronary artery (100%) and combination of left coronary artery & right coronary artery (18.1%). 8) Duation of fever, positive CRP & WBC count were statistically higher in patients with coronary aneurysm than in patients without coronary aneurysm.
Key Words: Mucocutaneous lymph node syndrome

METRICS Graph View
  • 1,261 View
  • 4 Download