| Thyroid function Study in Respiratory distress Syndrome. |
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Sung Soo Kong, Mi Young Chung, Dong Hyunk Kum |
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Department of Pediatrics, Koryo General Hospital, Seoul, Korea |
| 호흡곤란증후군 환아의 갑상선기능에 관한 연구 |
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공성수, 정미영, 금동혁 |
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고려병원 소아과 |
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Received: 3 May 1990 • Accepted: 2 July 1990 |
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| Abstract |
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It has been known that intrauterine thyroid hormone deficiency may be one of the factors predis-
posing to RDS in premature infants. L-thyroxine has been shown to increase the production opf lung
surfactant, widely accepted as deficient in RDS infants, as association between lung immaturity and
fetal thyroid function is postulated. The authors investigated thyroid hormone concentration at birth
and 5, 15 days of age, in healthy premature infants and RDS infants.
The results were as follows:
1) At birth, infants with RDS had significantly lower serum levels of T3 compare to healthy
premature infants, but T4, TSH, T4RU, FT4I was slightly decreased.
2) At 5 days of age, infants with RDS showed significantly lower serum levels of T3, T4, FT4I, but
TSH and T3RU were not significant difference.
3) At 15 days of age, infants with RDS and healthy premature infants were not significant
differance.
The thyroid hormone concentrations at birth and at 15 days of age in preterm infants suffering RDS
were comparable with those observed in healthy premature infants, whereas the day 5 T3, T4
concentrations and FT4I values were significantly lower.
TSH concentrations were normal at each sampling interval. These observations support the view
that the postnatal depression of thyroid function is secondary to respiratory distress syndrome. |
| Key Words:
Respiratory distress syndrome, Thyroid hormone |
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