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A Case of Nonimmunologic Hydrops Fetalis Associated with Down Syndrome.

Journal of the Korean Pediatric Society 1990;33(2):205-211.
Published online February 28, 1990.
A Case of Nonimmunologic Hydrops Fetalis Associated with Down Syndrome.
Sang Eun Lee, Meen Jai Lee, Dong Hwan Lee, Sang Jhoo Lee
Department of Pediatrics, College of Medicine, Soon Chun Hyang University, Seoul, Korea
Down 증후군에 동반된 비면역성 태아수종 1례
이상은, 이민재, 이동환, 이상주
순천향의과대학 소아과학교실
Received: 29 June 1989   • Accepted: 19 September 1989
We experienced a case of nonimmunologic hydrops fetalis associated with Down syndrome. The patient had generalized edema with severe scrotal swelling and abdominal distension. A roentgenogram showed bilateral pleural effusion and ascites. The chromosomal study revealed 21 trisomy. On autopsy, there were pleural fluid and ascites as well as pericardial fluid. Small ASD and incomplete lobation of the right lung were detected. Chromosomal abnormalities should always be considered in the differential diagnosis of nonim- munologic hydrops fetalis in the fetus and neonate. Their features are often distorted by edema, thus obscuring the phenotypic characteristics of the common chromosomal abnormalities.
Key Words: Nonimmunologic hydrops fetalis, Chromosome, Down syndrome

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