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Hypertrophic Cardiomyopathy in Infant of Diabetic Mother.

Journal of the Korean Pediatric Society 1989;32(8):1138-1143.
Published online August 31, 1989.
Hypertrophic Cardiomyopathy in Infant of Diabetic Mother.
Jeong Sam Jeon, Soo Chun Kim, Chong Woo Bae, Sung Ho Cha, Chang Il Ahn
Department of Pediatraics, College of Medicine, Kyung Hee University, Seoul, Korea
당뇨병 모체에서 태어난 신생아에서의 비후성 심근증 1례
전정삼, 김수천, 배종우, 차성호, 안창일
경희대학교 의과대학 소아과학교실
Received: 25 January 1989   • Accepted: 20 March 1989
Generally, infant of diabetic mother (IDM) have complex multisystems disease resulting in a high incidence of perinatal morbidity and mortality. Hypertrophic cardiomyopathy (HCM)-IDM appears as the early onset, transient and non-familial cariomyopathy in neonatal period. The etiology of the left ventricular outflow obstruction in these neonates is not clear. But, it is possible that the asymmetrical septal hypertrophy was a manifestation of the generalized organomegaly. The natural history of HCM-IDM appears to be benign with a spontaneous resolution of symtoms within 1 to 4 weeks and a spontaneous resolution of septal hypertrophy within 3 to 5 months. Most of the infants need only supportive care. We experienced 1 case of HCM-IDM in a male newborn who was delivered to a 27 years old woman by cesarean section with birth weight 5000 gm. His mother has been suffering from class B diabetes. We confirmed HCM-IDM on clinical manifestation, EKG, and echocardiogram. A review of literatures was also attempted briefly.
Key Words: Hypertrophic cardiomyopathy, Infant of diabetic mother

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